Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapour.
Identifieur interne : 000658 ( Main/Exploration ); précédent : 000657; suivant : 000659Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapour.
Auteurs : E M Erfurth [Suède] ; A. Schütz ; A. Nilsson ; L. Barreg Rd ; S. SkerfvingSource :
- British journal of industrial medicine [ 0007-1072 ] ; 1990.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Dentistes (MeSH), Exposition environnementale (MeSH), Exposition professionnelle (MeSH), Hormone folliculostimulante (sang), Hormone lutéinisante (sang), Hormones antéhypophysaires (métabolisme), Hormones hypophysiotropes libératrices (MeSH), Humains (MeSH), Hydrocortisone (sang), Hypophyse (effets des médicaments et des substances chimiques), Hypophyse (métabolisme), Mercure (effets indésirables), Mercure (sang), Mâle (MeSH), Prolactine (sang), Sélénium (sang), Thyréostimuline (sang).
- MESH :
- effets des médicaments et des substances chimiques : Hypophyse.
- effets indésirables : Mercure.
- métabolisme : Hormones antéhypophysaires, Hypophyse.
- sang : Hormone folliculostimulante, Hormone lutéinisante, Hydrocortisone, Mercure, Prolactine, Sélénium, Thyréostimuline.
- Adulte, Adulte d'âge moyen, Dentistes, Exposition environnementale, Exposition professionnelle, Hormones hypophysiotropes libératrices, Humains, Mâle.
English descriptors
- KwdEn :
- Adult (MeSH), Dentists (MeSH), Environmental Exposure (MeSH), Follicle Stimulating Hormone (blood), Humans (MeSH), Hydrocortisone (blood), Luteinizing Hormone (blood), Male (MeSH), Mercury (adverse effects), Mercury (blood), Middle Aged (MeSH), Occupational Exposure (MeSH), Pituitary Gland (drug effects), Pituitary Gland (metabolism), Pituitary Hormone-Releasing Hormones (MeSH), Pituitary Hormones, Anterior (metabolism), Prolactin (blood), Selenium (blood), Thyrotropin (blood).
- MESH :
- chemical , adverse effects : Mercury.
- chemical , blood : Follicle Stimulating Hormone, Hydrocortisone, Luteinizing Hormone, Mercury, Prolactin, Selenium, Thyrotropin.
- drug effects : Pituitary Gland.
- metabolism : Pituitary Gland, Pituitary Hormones, Anterior.
- Adult, Dentists, Environmental Exposure, Humans, Male, Middle Aged, Occupational Exposure, Pituitary Hormone-Releasing Hormones.
Abstract
Exposure to elemental mercury (Hg) vapour results in an accumulation of Hg in the pituitary, the thyroid, and the testis. In this study, basal serum concentrations of pituitary hormones (thyrotrophin (TSH), prolactin (PRL), follicle stimulating hormone (FSH), and luteinising hormone (LH] or their response after administration of thyrotrophin and gonadotrophin releasing hormones did not differ between 11 male workers (mean urinary Hg (U Hg) concentration 26 nmol/mmol creatinine) and nine male dentists (U Hg concentration 1.3 nmol/mmol creatinine) exposed to elemental Hg vapour when compared with matched referent groups (U Hg concentration 0.6 and 0.4 nmol/mmol creatinine). Thus there was no evidence of an effect of Hg on the pituitary. Neither was there any association between exposure to Hg and serum concentrations of free thyroid hormones (S FT3, S FT4), testosterone, or cortisol. Increased plasma concentrations of selenium (Se) were associated with increased basal serum concentrations of TSH, decreased concentrations of basal serum cortisol, and decreased release of FSH.
DOI: 10.1136/oem.47.9.639
PubMed: 2119795
PubMed Central: PMC1035251
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Schütz</name></author><author><name sortKey="Nilsson, A" sort="Nilsson, A" uniqKey="Nilsson A" first="A" last="Nilsson">A. Nilsson</name></author><author><name sortKey="Barreg Rd, L" sort="Barreg Rd, L" uniqKey="Barreg Rd L" first="L" last="Barreg Rd">L. Barreg Rd</name></author><author><name sortKey="Skerfving, S" sort="Skerfving, S" uniqKey="Skerfving S" first="S" last="Skerfving">S. 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In this study, basal serum concentrations of pituitary hormones (thyrotrophin (TSH), prolactin (PRL), follicle stimulating hormone (FSH), and luteinising hormone (LH] or their response after administration of thyrotrophin and gonadotrophin releasing hormones did not differ between 11 male workers (mean urinary Hg (U Hg) concentration 26 nmol/mmol creatinine) and nine male dentists (U Hg concentration 1.3 nmol/mmol creatinine) exposed to elemental Hg vapour when compared with matched referent groups (U Hg concentration 0.6 and 0.4 nmol/mmol creatinine). Thus there was no evidence of an effect of Hg on the pituitary. Neither was there any association between exposure to Hg and serum concentrations of free thyroid hormones (S FT3, S FT4), testosterone, or cortisol. Increased plasma concentrations of selenium (Se) were associated with increased basal serum concentrations of TSH, decreased concentrations of basal serum cortisol, and decreased release of FSH.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2119795</PMID><DateCompleted><Year>1990</Year><Month>11</Month><Day>13</Day></DateCompleted><DateRevised><Year>2019</Year><Month>05</Month><Day>03</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0007-1072</ISSN><JournalIssue CitedMedium="Print"><Volume>47</Volume><Issue>9</Issue><PubDate><Year>1990</Year><Month>Sep</Month></PubDate></JournalIssue><Title>British journal of industrial medicine</Title><ISOAbbreviation>Br J Ind Med</ISOAbbreviation></Journal><ArticleTitle>Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapour.</ArticleTitle><Pagination><MedlinePgn>639-44</MedlinePgn></Pagination><Abstract><AbstractText>Exposure to elemental mercury (Hg) vapour results in an accumulation of Hg in the pituitary, the thyroid, and the testis. In this study, basal serum concentrations of pituitary hormones (thyrotrophin (TSH), prolactin (PRL), follicle stimulating hormone (FSH), and luteinising hormone (LH] or their response after administration of thyrotrophin and gonadotrophin releasing hormones did not differ between 11 male workers (mean urinary Hg (U Hg) concentration 26 nmol/mmol creatinine) and nine male dentists (U Hg concentration 1.3 nmol/mmol creatinine) exposed to elemental Hg vapour when compared with matched referent groups (U Hg concentration 0.6 and 0.4 nmol/mmol creatinine). Thus there was no evidence of an effect of Hg on the pituitary. Neither was there any association between exposure to Hg and serum concentrations of free thyroid hormones (S FT3, S FT4), testosterone, or cortisol. Increased plasma concentrations of selenium (Se) were associated with increased basal serum concentrations of TSH, decreased concentrations of basal serum cortisol, and decreased release of FSH.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Erfurth</LastName><ForeName>E M</ForeName><Initials>EM</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, University Hospital, Lund, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schütz</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Nilsson</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Barregård</LastName><ForeName>L</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Skerfving</LastName><ForeName>S</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Br J Ind Med</MedlineTA><NlmUniqueID>0370637</NlmUniqueID><ISSNLinking>0007-1072</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010906">Pituitary Hormone-Releasing Hormones</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010908">Pituitary Hormones, Anterior</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-62-4</RegistryNumber><NameOfSubstance UI="D011388">Prolactin</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-67-9</RegistryNumber><NameOfSubstance UI="D007986">Luteinizing Hormone</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-68-0</RegistryNumber><NameOfSubstance UI="D005640">Follicle Stimulating Hormone</NameOfSubstance></Chemical><Chemical><RegistryNumber>9002-71-5</RegistryNumber><NameOfSubstance UI="D013972">Thyrotropin</NameOfSubstance></Chemical><Chemical><RegistryNumber>FXS1BY2PGL</RegistryNumber><NameOfSubstance UI="D008628">Mercury</NameOfSubstance></Chemical><Chemical><RegistryNumber>H6241UJ22B</RegistryNumber><NameOfSubstance UI="D012643">Selenium</NameOfSubstance></Chemical><Chemical><RegistryNumber>WI4X0X7BPJ</RegistryNumber><NameOfSubstance UI="D006854">Hydrocortisone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003815" MajorTopicYN="N">Dentists</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004781" MajorTopicYN="N">Environmental Exposure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005640" MajorTopicYN="N">Follicle Stimulating Hormone</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006854" MajorTopicYN="N">Hydrocortisone</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007986" MajorTopicYN="N">Luteinizing Hormone</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008628" MajorTopicYN="N">Mercury</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle 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sortKey="Barreg Rd, L" sort="Barreg Rd, L" uniqKey="Barreg Rd L" first="L" last="Barreg Rd">L. Barreg Rd</name><name sortKey="Nilsson, A" sort="Nilsson, A" uniqKey="Nilsson A" first="A" last="Nilsson">A. Nilsson</name><name sortKey="Schutz, A" sort="Schutz, A" uniqKey="Schutz A" first="A" last="Schütz">A. Schütz</name><name sortKey="Skerfving, S" sort="Skerfving, S" uniqKey="Skerfving S" first="S" last="Skerfving">S. Skerfving</name></noCountry><country name="Suède"><noRegion><name sortKey="Erfurth, E M" sort="Erfurth, E M" uniqKey="Erfurth E" first="E M" last="Erfurth">E M Erfurth</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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